Living nano-micro fibrous woven fabric/hydrogel composite scaffolds for heart valve engineering
نویسندگان
چکیده
منابع مشابه
Electrospun Scaffolds for Heart Valve Tissue Engineering
INTRODUCTION Heart valve replacements are required for a number of heart diseases and replacements, as well as for both pediatric and adult populations. It is estimated that 2.5% of the population has valvular heart disease [1], and annually, over 250,000 people worldwide receive heart valve replacements [1]. Tissue engineering (TE) strategies hold the most promise for permanently restoring the...
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متن کاملTri-layered elastomeric scaffolds for engineering heart valve leaflets.
Tissue engineered heart valves (TEHVs) that can grow and remodel have the potential to serve as permanent replacements of the current non-viable prosthetic valves particularly for pediatric patients. A major challenge in designing functional TEHVs is to mimic both structural and anisotropic mechanical characteristics of the native valve leaflets. To establish a more biomimetic model of TEHV, we...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2017
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2017.01.051